Doses of weak dopamine antagonists diffuse to depress receptors such that dopamine neurotransmitter molecules cannot reach their starting line at the axons' dopamine neuroreceptors that transmit nerve impulses. Cannabis is then according to the runnings of the Grand Prix of neuroreception, a jnana crash.
Bhakti is knowledge ordinately governed by discrimination and is caused by serotonin, often called the grease that makes our entire central nervous systems run smoothly. Serotonin elicits endearment, gift giving, and higher thresholds of pain tolerance than endorphins. Dogs have much more serotoninergic activity in their wild counterparts.
Slumdog outsiders with a serotonin deficit lack socialization and care from close companions and are apt to mistakenly ignore the expectations of challenges. Dopamine is, however, essential for movement and thinking, and to comprehend social meaning and recognize those around them; the perfect example being the patients of Alzheimer's disease and Parkinson's who cannot remember social situations or coordinate movements.