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Saturday, September 18, 2010

Osteoarthritis and Glucosamines

In The Textbook of Natural Medicine Drs. Pizzony and Murray suggest the following for people suffering from osteoarthritis:
Glucosamine sulfate: 1500mgs/day
Vitamin E: 600IU/day
Vitamin A: 5000IU/day
Vitamin C: 1-3g/day
Vitamin B6: 50mg/day
Pantothenic acid: 12.5mgs/day
Methionine: 400mgs three times a day
Zinc: 45mg/day
Copper: 1mg/day

The glucosamine sulfate is particularly important: studies show that both ibuprofen and glucosamine sulfate reduce the pain of osteoarthritis but that glucosamine sulfate is more effective. Glucosamine is an amino sugar, a molecule composed of an amino acid and a simple sugar. Just as amino acids are the building blocks of proteins, amino sugars are the building blocks of molecules called 'glycosaminoglycans'. Amino sugars are used in the assembly of tissue components; they are the structural basis of connective tissues and lubricating fluids. Glycosaminogylcans are found in all connective tissue and mucous membranes; glucosamine macromolecules are the basic substrate of cartilage, ligaments, tendons and bones

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